TFAP4, transcription factor AP-4

TFAP4, transcription factor AP-4

• Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]

• Gene Synonyms (transcription factor AP-4, activating enhancer-binding protein 4, class C basic helix-loop-helix protein 41, transcription factor AP-4 (activating enhancer binding protein 4), AP-4, bHLHc41,)
• NCBI Gene ID: 7023
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q01664
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription factor AP-4 interacts with:

• ADAM metallopeptidase with thrombospondin type 1 motif 4
  ajuba LIM protein
  angiopoietin like 7
  AT-rich interaction domain 1A
  AT-rich interaction domain 2
  beta-transducin repeat containing E3 ubiquitin protein ligase
  bromodomain containing 7
  B-TFIID TATA-box binding protein associated factor 1
  calcineurin binding protein 1
  CCCTC-binding factor
  CDKN2A interacting protein
  chromatin accessibility complex subunit 1
  clock circadian regulator
  CST telomere replication complex component 1
  cullin 1
  cytoskeleton associated protein 5
  deoxynucleotidyltransferase terminal interacting protein 1
  DExD-box helicase 39B
  DNA topoisomerase II binding protein 1
  euchromatic histone lysine methyltransferase 1
  euchromatic histone lysine methyltransferase 2
  exosome component 8
  F-box and WD repeat domain containing 11
  F-box and WD-40 domain protein 11
  F-box protein 38
  forkhead box K1
  G protein subunit beta 4
  H4 clustered histone 1
  histone cell cycle regulator
  histone PARylation factor 1
  inhibitor of CDK, cyclin A1 interacting protein 1
  INO80 complex subunit E
  mediator of DNA damage checkpoint 1
  metastasis associated 1 family member 3
  methyl-CpG binding domain protein 2
  microspherule protein 1
  mitotic arrest deficient 2 like 2
  mitotic deacetylase associated SANT domain protein
  neuron navigator 3
  neuronal guanine nucleotide exchange factor
  nuclear receptor subfamily 2 group F member 1
  nuclear receptor subfamily 2 group F member 2
  poly(ADP-ribose) polymerase 2
  potassium channel tetramerisation domain containing 5
  potassium channel tetramerization domain containing 2
  PR/SET domain 16
  protein phosphatase 6 regulatory subunit 3
  RAD50 double strand break repair protein
  Scm like with four mbt domains 2
  SIN3 transcription regulator family member A
  SIN3 transcription regulator family member B
  Sin3A associated protein 130
  small nuclear ribonucleoprotein U5 subunit 200
  SOGA family member 3
  STN1 subunit of CST complex
  tektin 4
  TERF2 interacting protein
  thymocyte nuclear protein 1
  TNF receptor associated factor 1
  TNF receptor associated factor 4
  transcription factor CP2
  transcription factor CP2 like 1
  transcription termination factor 2
  tribbles pseudokinase 2
  tumor protein p53
  ubinuclein 2
  ubiquitin like with PHD and ring finger domains 2
  upstream binding protein 1
  upstream transcription factor 2, c-fos interacting
  vimentin type intermediate filament associated coiled-coil protein
  VRK serine/threonine kinase 1
  WD repeat domain 45B
  WIZ zinc finger
  X-ray repair cross complementing 5
  YEATS domain containing 2
  zinc finger and BTB domain containing 7A
  zinc finger and BTB domain containing 7B
  zinc finger protein 335
  zinc finger protein 462
  zinc finger ZZ-type containing 3
  zinc fingers and homeoboxes 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.