JMJD6, jumonji domain containing 6, arginine demethylase and lysine hydroxylase

JMJD6, jumonji domain containing 6, arginine demethylase and lysine hydroxylase

• This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (PSR, PTDSR, PTDSR1, bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, arginine demethylase and lysine hydroxylase, histone arginine demethylase JMJD6, jmjC domain-containing protein 6, jumonji domain containing 6, jumonji domain-containing protein 6, lysyl-hydroxylase JMJD6, peptide-lysine 5-dioxygenase JMJD6, phosphatidylserine receptor,)
• NCBI Gene ID: 23210
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6NYC1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

jumonji domain containing 6, arginine demethylase and lysine hydroxylase interacts with:

• ADP ribosylation factor like GTPase 6 interacting protein 4
  AE binding protein 2
  ankyrin repeat and EF-hand domain containing 1
  arginine and glutamate rich 1
  arginine and serine rich coiled-coil 1
  arginine and serine rich coiled-coil 2
  autophagy related 16 like 1
  bromodomain containing 4
  cactin, spliceosome C complex subunit
  caspase activity and apoptosis inhibitor 1
  CDC like kinase 4
  cell division cycle associated 2
  centromere protein L
  chromosome 17 open reading frame 97
  cleavage and polyadenylation specific factor 7
  cullin associated and neddylation dissociated 1
  cyclin L1
  cyclin L2
  cysteine and histidine rich 1
  DEAH-box helicase 40
  family with sequence similarity 9 member A
  FERM domain containing 6
  FYVE, RhoGEF and PH domain containing 5
  integrator complex subunit 13
  La ribonucleoprotein 7, transcriptional regulator
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  LUC7 like 3 pre-mRNA splicing factor
  N-alpha-acetyltransferase 50, NatE catalytic subunit
  NFKB activating protein
  NHP2 ribonucleoprotein
  NKAP domain containing 1
  nuclear assembly factor 1 ribonucleoprotein
  nuclear speckle splicing regulatory protein 1
  PAX3 and PAX7 binding protein 1
  peptidylprolyl isomerase like 4
  PHD and ring finger domains 1
  pre-mRNA processing factor 38A
  pre-mRNA processing factor 38B
  pre-mRNA processing factor 40 homolog A
  RAB, member RAS oncogene family like 6
  RAN binding protein 6
  ring finger protein 138
  RNA binding motif protein 23
  RNA binding motif protein 25
  RNA binding motif protein 26
  RNA binding motif protein 27
  RNA binding motif protein X-linked 2
  RNA binding region (RNP1, RRM) containing 3
  R-spondin 2
  schlafen family member 12
  SET domain containing 2, histone lysine methyltransferase
  SH3 and cysteine rich domain 3
  splicing regulatory glutamic acid and lysine rich protein 1
  SR-related CTD associated factor 1
  SR-related CTD associated factor 4
  tuftelin interacting protein 11
  U2 snRNP associated SURP domain containing
  ubiquitin specific peptidase 42
  VPS29 retromer complex component
  WD repeat domain 33
  WD repeat domain 48
  zinc finger CCCH-type containing 4
  zinc finger CCHC-type containing 17
  zinc finger MYM-type containing 1
  zinc finger protein 451

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.