GATA1, GATA binding protein 1

GATA1, GATA binding protein 1

• This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, erythroid transcription factor, GATA-binding factor 1, NF-E1 DNA-binding protein, erythroid transcription factor 1, globin transcription factor 1, nuclear factor, erythroid 1, transcription factor GATA1,)
• NCBI Gene ID: 2623
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P15976
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GATA binding protein 1 interacts with:

• alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  armadillo repeat containing 7
  ATPase H+ transporting V0 subunit d1
  AT-rich interaction domain 1A
  chordin
  coiled-coil domain containing 24
  DEAH-box helicase 36
  DiGeorge syndrome critical region gene 6 like
  DNA methyltransferase 3 like
  FA complementation group L
  Fas binding factor 1
  fibroblast growth factor receptor substrate 3
  glutaredoxin 3
  golgin A2
  GRB2 related adaptor protein 2
  heat shock protein family A (Hsp70) member 4
  heat shock protein family B (small) member 1
  hemogen
  hes related family bHLH transcription factor with YRPW motif 1
  HEXIM P-TEFb complex subunit 2
  histone deacetylase 1
  histone deacetylase 3
  histone deacetylase 4
  histone deacetylase 5
  homeobox A1
  IKAROS family zinc finger 1
  keratin associated protein 10-5
  keratin associated protein 3-2
  keratin associated protein 4-11
  keratin associated protein 4-5
  keratin associated protein 9-2
  KN motif and ankyrin repeat domains 2
  leucine zipper tumor suppressor 2
  LIM domain only 2
  makorin ring finger protein 3
  mediator complex subunit 1
  mediator complex subunit 14
  mediator complex subunit 17
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 3
  mitogen-activated protein kinase 6
  MyoD family inhibitor
  NME/NM23 nucleoside diphosphate kinase 1
  paired like homeodomain 1
  phospholipid scramblase 4
  PML nuclear body scaffold
  PNMA family member 1
  proteasome inhibitor subunit 1
  protein kinase AMP-activated catalytic subunit alpha 1
  protein kinase AMP-activated non-catalytic subunit beta 2
  protein phosphatase 1 regulatory subunit 16B
  proteoglycan 2, pro eosinophil major basic protein
  Rap associating with DIL domain
  Ras and Rab interactor 3
  RB transcriptional corepressor 1
  retinoic acid induced 1
  RNA binding protein, mRNA processing factor
  signal transducer and activator of transcription 3
  SKI proto-oncogene
  Sp1 transcription factor
  Spi-1 proto-oncogene
  Spi-B transcription factor
  steroid receptor RNA activator 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
  TAL bHLH transcription factor 1, erythroid differentiation factor
  TATA-box binding protein associated factor 7
  Tax1 binding protein 3
  tektin 4
  tensin 2
  thyroid hormone receptor interactor 6
  TNF receptor associated factor 1
  tripartite motif containing 25
  tripartite motif containing 29
  ubiquitin specific peptidase 7
  zinc finger and BTB domain containing 16
  zinc finger and BTB domain containing 22
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 521
  zinc finger protein, FOG family member 1
  zinc finger protein, FOG family member 2
  zinc finger ZZ-type containing 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.