MAD2L1, mitotic arrest deficient 2 like 1

MAD2L1, mitotic arrest deficient 2 like 1

• MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HSMAD2, MAD2, mitotic spindle assembly checkpoint protein MAD2A, MAD2 (mitotic arrest deficient, yeast, homolog)-like 1, MAD2 mitotic arrest deficient-like 1, MAD2-like protein 1, mitotic arrest deficient 2-like protein 1, mitotic arrest deficient, yeast, homolog-like 1,)
• NCBI Gene ID: 4085
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13257
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitotic arrest deficient 2 like 1 interacts with:

• AAR2 splicing factor
  ADAM metallopeptidase domain 15
  ADAM metallopeptidase domain 17
  anaphase promoting complex subunit 1
  anaphase promoting complex subunit 2
  anaphase promoting complex subunit 2
  anaphase promoting complex subunit 4
  anaphase promoting complex subunit 7
  ataxin 3
  ATP binding cassette subfamily F member 2
  BAF chromatin remodeling complex subunit BCL7C
  BAG cochaperone 5
  BUB1B, mitotic checkpoint serine/threonine kinase
  BUB3 mitotic checkpoint protein
  CDC16 cell division cycle 16
  CDC23 cell division cycle 23
  cell division cycle 16
  cell division cycle 20
  cell division cycle 26
  charged multivesicular body protein 2B
  checkpoint with forkhead and ring finger domains
  CTD phosphatase subunit 1
  CUE domain containing 2
  cullin 3
  DEP domain containing 5, GATOR1 subcomplex subunit
  dual serine/threonine and tyrosine protein kinase
  dynein light chain LC8-type 1
  egl-9 family hypoxia inducible factor 3
  EPM2A interacting protein 1
  F-box protein 6
  filaggrin family member 2
  H3 clustered histone 1
  importin 7
  kelch like ECH associated protein 1
  kelch like family member 13
  kinesin family member 20A
  MAD2 mitotic arrest deficient-like 1
  MAD2L1 binding protein
  MAD2L1 binding protein
  mannose binding lectin 2
  methylphosphate capping enzyme
  microtubule actin crosslinking factor 1
  mitotic arrest deficient 1 like 1
  mitotic arrest deficient 2 like 1
  mitotic arrest deficient 2 like 2
  NDC80 kinetochore complex component
  nicastrin
  NIMA related kinase 2
  NSL1 component of MIS12 kinetochore complex
  nuclear receptor subfamily 2 group C member 2
  nucleoporin 98 and 96 precursor
  nudix hydrolase 5
  oxidative stress responsive kinase 1
  pleckstrin homology domain containing A4
  prohibitin
  proteasome 26S subunit, non-ATPase 8
  protein phosphatase 1 regulatory subunit 9A
  protein phosphatase, Mg2+/Mn2+ dependent 1E
  PYM homolog 1, exon junction complex associated factor
  Rab acceptor 1
  Raf-1 proto-oncogene, serine/threonine kinase
  REV3 like, DNA directed polymerase zeta catalytic subunit
  ribosomal protein S3A
  ring finger protein 2
  ring finger protein 4
  solute carrier family 39 member 7
  syndecan binding protein
  thyroid hormone receptor interactor 13
  TNF receptor associated protein 1
  torsin 1A interacting protein 1
  tRNA methyltransferase 10A
  TSC22 domain family member 4
  tubulin beta class I
  tumor protein p73
  ubiquitin conjugating enzyme E2 C
  ubiquitin D
  WD repeat domain 35
  zw10 kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.