CHMP1A, charged multivesicular body protein 1A

CHMP1A, charged multivesicular body protein 1A

• This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

• Gene Synonyms (CHMP1, PCH8, PCOLN3, PRSM1, VPS46-1, VPS46A, charged multivesicular body protein 1a, charged multivesicular body protein 1/chromatin modifying protein 1, chromatin modifying protein 1A, procollagen (type III) N-endopeptidase, protease, metallo, 1, 33kD, vacuolar protein sorting-associated protein 46-1,)
• NCBI Gene ID: 5119
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HD42
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

charged multivesicular body protein 1A interacts with:

• BRO1 domain and CAAX motif containing
  CD2-associated protein
  charged multivesicular body protein 1A
  charged multivesicular body protein 1B
  charged multivesicular body protein 2A
  charged multivesicular body protein 4B
  charged multivesicular body protein 4B
  charged multivesicular body protein 5
  chromosome 14 open reading frame 119
  complement component 1, q subcomponent binding protein
  cyclic GMP-AMP synthase
  DNA damage inducible transcript 4 like
  elongation factor Tu GTP binding domain containing 2
  F-box and leucine rich repeat protein 18
  golgi reassembly stacking protein 2
  golgi transport 1B
  hes related family bHLH transcription factor with YRPW motif 2
  IST1 factor associated with ESCRT-III
  kinase suppressor of ras 1
  LIM homeobox 4
  lunapark, ER junction formation factor
  microtubule interacting and trafficking domain containing 1
  nuclear receptor subfamily 1 group I member 2
  nuclear RNA export factor 1
  pleckstrin homology domain containing A4
  presenilin 1
  proteasome 20S subunit alpha 1
  protein tyrosine phosphatase, non-receptor type 23
  pyrin and HIN domain family member 1
  RAB5C, member RAS oncogene family
  RAB7A, member RAS oncogene family
  RAN binding protein 2
  RuvB-like protein 1
  SIX homeobox 2
  spastin
  STAM binding protein
  syndecan binding protein
  thioredoxin 2
  trafficking from ER to golgi regulator
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 8
  UFM1 specific ligase 1
  vacuolar protein sorting 4 homolog A
  vacuolar protein sorting 4 homolog B
  vacuolar protein sorting 4B
  vesicle trafficking 1
  visual system homeobox 2
  WW domain containing E3 ubiquitin protein ligase 2
  YES proto-oncogene 1, Src family tyrosine kinase
  zinc finger DHHC-type palmitoyltransferase 17
  zinc finger protein 524

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.