PFDN5, prefoldin subunit 5

PFDN5, prefoldin subunit 5

• This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (prefoldin subunit 5, c-myc binding protein, myc modulator-1, MM-1, MM1, PFD5,)
• NCBI Gene ID: 5204
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99471
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prefoldin subunit 5 interacts with:

• abl interactor 2
  actin related protein 2/3 complex subunit 2
  alanyl-tRNA synthetase domain containing 1
  ankyrin repeat domain 55
  arginine and serine rich coiled-coil 2
  armadillo repeat containing 6
  basic helix-loop-helix family member e40
  BCAS2 pre-mRNA processing factor
  beta-transducin repeat containing E3 ubiquitin protein ligase
  BRMS1 transcriptional repressor and anoikis regulator
  calcium binding and coiled-coil domain 2
  centrosome and spindle pole associated protein 1
  chaperonin containing TCP1 subunit 8
  chromosome 10 open reading frame 62
  chromosome 20 open reading frame 85
  chromosome 22 open reading frame 39
  chromosome 4 open reading frame 45
  chromosome 7 open reading frame 31
  coiled-coil domain containing 198
  complexin 1
  cullin 2
  DDB1 and CUL4 associated factor 5
  DDB1 and CUL4 associated factor 7
  docking protein 4
  docking protein 5
  doublesex and mab-3 related transcription factor 3
  EEF1A lysine methyltransferase 3
  elongin B
  espin like
  exportin 5
  FA core complex associated protein 20
  family with sequence similarity 102 member A
  family with sequence similarity 110 member A
  family with sequence similarity 214 member B
  family with sequence similarity 221 member A
  family with sequence similarity 222 member B
  family with sequence similarity 90 member A1
  F-box and WD repeat domain containing 11
  F-box and WD repeat domain containing 4
  F-box and WD repeat domain containing 8
  G protein subunit beta 5
  G1 to S phase transition 1
  glutaredoxin 3
  glutathione S-transferase omega 2
  glycerate kinase
  golgi phosphoprotein 3
  G-patch domain and ankyrin repeats 1
  guanylyl cyclase domain containing 1
  hyaluronan and proteoglycan link protein 2
  IKAROS family zinc finger 3
  importin 7
  inhibitor of CDK, cyclin A1 interacting protein 1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  intersectin 1
  iroquois homeobox 2
  iroquois homeobox 6
  kelch domain containing 2
  kelch like family member 38
  kelch like family member 42
  L3MBTL histone methyl-lysine binding protein 2
  La ribonucleoprotein 4
  ligand of numb-protein X 1
  lysine demethylase 1A
  Max protein
  methyltransferase like 21A
  mitochondrial ribosomal protein L45
  mitogen-activated protein kinase 7
  mitogen-activated protein kinase kinase 5
  mitotic spindle positioning
  MTOR associated protein, LST8 homolog
  myotilin
  myozenin 1
  NADPH oxidase activator 1
  neurogenin 2
  NGG1 interacting factor 3 like 1
  NOP2/Sun RNA methyltransferase 2
  N-terminal glutamine amidase 1
  paired immunoglobin like type 2 receptor alpha
  paired like homeodomain 1
  paired like homeodomain 2
  PHD finger protein 1
  PHD finger protein 24
  POC1 centriolar protein A
  POC1 centriolar protein B
  pogo transposable element derived with ZNF domain
  polycomb group ring finger 3
  potassium channel tetramerization domain containing 9
  POZ/BTB and AT hook containing zinc finger 1
  prefoldin 2
  prefoldin subunit 6
  pre-mRNA processing factor 18
  pre-mRNA processing factor 4
  proline rich 35
  proteasome 20S subunit beta 4
  proteasome 20S subunit beta 8
  proteasome 26S subunit, ATPase 4
  proteasome 26S subunit, non-ATPase 8
  proteasome activator subunit 3
  protein disulfide isomerase family A member 6
  protein kinase AMP-activated non-catalytic subunit beta 2
  protein kinase cAMP-dependent type I regulatory subunit alpha
  protein phosphatase 1 regulatory subunit 32
  protein phosphatase 2 catalytic subunit beta
  protein phosphatase 2 regulatory subunit B'delta
  protein phosphatase 3 catalytic subunit alpha
  protein phosphatase 6 regulatory subunit 1
  protein phosphatase 6 regulatory subunit 2
  pseudouridine synthase 1
  regulation of nuclear pre-mRNA domain containing 1B
  replication protein A1
  RIB43A domain with coiled-coils 1
  ring finger and CCCH-type domains 2
  ring finger protein 115
  ripply transcriptional repressor 1
  RUN and SH3 domain containing 1
  serine/threonine kinase 19
  serine/threonine/tyrosine interacting like 1
  SH3 domain containing GRB2 like 1, endophilin A2
  shisa family member 6
  SIN3 transcription regulator family member A
  SLAIN motif family member 1
  small ArfGAP 1
  small nuclear ribonucleoprotein polypeptides B and B1
  small nuclear ribonucleoprotein U11/U12 subunit 25
  SMG9 nonsense mediated mRNA decay factor
  snail family transcriptional repressor 1
  sodium channel modifier 1
  Sp1 transcription factor
  sperm associated antigen 8
  spermatogenesis and oogenesis specific basic helix-loop-helix 1
  spermatogenesis associated 5
  SPG21 abhydrolase domain containing, maspardin
  S-phase kinase associated protein 2
  stabilizer of axonemal microtubules 1
  synaptonemal complex central element protein 1 like
  synaptotagmin 17
  syndecan binding protein
  TATA-box binding protein associated factor 6 like
  T-box transcription factor 3
  TRAF family member associated NFKB activator
  trafficking from ER to golgi regulator
  trafficking protein particle complex 6A
  transcription factor 19
  tripartite motif containing 28
  tubulin alpha 1a
  tubulin alpha 1b
  tubulin alpha 3c
  tubulin alpha 3e
  tubulin gamma 1
  tubulin, beta 4B class IVB
  tumor protein p73
  URI1 prefoldin like chaperone
  vascular endothelial zinc finger 1
  ventral anterior homeobox 2
  vestigial like family member 1
  VHL binding protein 1
  vir like m6A methyltransferase associated
  von Hippel-Lindau binding protein 1
  WD repeat domain 25
  yippee like 5
  zinc finger C2HC-type containing 1C
  zinc finger protein 148

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.