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TANK, TRAF family member associated NFKB activator

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TANK, TRAF family member associated NFKB activator

  • The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

  • Gene Synonyms (TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, I-TRAF, ITRAF, TRAF2,)
  • NCBI Gene ID: 10010
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>B2R7S3
    UNIPROT ID#>>Q92844
    UNIPROT ID#>>Q6NW12
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TRAF family member associated NFKB activator interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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