AP3D1, adaptor related protein complex 3 subunit delta 1

AP3D1, adaptor related protein complex 3 subunit delta 1

• The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017]

• Gene Synonyms (AP-3 complex subunit delta-1, AP-3 complex delta subunit, partial CDS, adapter-related protein complex 3 subunit delta-1, adaptor related protein complex 3 delta 1 subunit, delta adaptin, subunit of putative vesicle coat adaptor complex AP-3, ADTD, HPS10, hBLVR,)
• NCBI Gene ID: 8943
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14617
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adaptor related protein complex 3 subunit delta 1 interacts with:

• adaptor related protein complex 3 subunit mu 1
  adaptor related protein complex 3 subunit mu 2
  adaptor related protein complex 3 subunit sigma 2
  anterior gradient 2, protein disulphide isomerase family member
  argonaute RISC catalytic component 3
  bromodomain containing 7
  BTB domain containing 8
  cell division cycle 73
  centromere protein J
  centrosomal protein 19
  COPI coat complex subunit gamma 1
  dystrobrevin binding protein 1
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  erythrocyte membrane protein band 4.1 like 3
  F-box and WD repeat domain containing 7
  HIV-1 Tat specific factor 1
  integrin alpha FG-GAP repeat containing 1
  kinesin light chain 2
  ninein
  peroxisome proliferator activated receptor gamma
  pleckstrin homology domain containing A4
  ring finger protein 13
  RNA binding motif protein 25
  RUN and FYVE domain containing 1
  solute carrier family 15 member 3
  trans-golgi network protein 2
  transmembrane protein 63A
  tripartite motif containing 28
  two pore segment channel 2
  vir like m6A methyltransferase associated
  VPS11, CORVET/HOPS core subunit
  VPS18 CORVET/HOPS core subunit
  VPS33A core subunit of CORVET and HOPS complexes
  VPS33B late endosome and lysosome associated
  VPS39 subunit of HOPS complex
  VPS41 subunit of HOPS complex
  VSP16 CORVET/HOPS core subunit

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.