PTGER3, prostaglandin E receptor 3

PTGER3, prostaglandin E receptor 3

• The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

• Gene Synonyms (prostaglandin E2 receptor EP3 subtype, PGE receptor, EP3 subtype, PGE2 receptor EP3 subtype, prostaglandin E receotor EP3 subtype 3 isoform, prostaglandin E receptor 3 (subtype EP3), prostaglandin receptor (PGE-2), prostanoid EP3 receptor, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3-VI, EP3e, PGE2-R, lnc003875,)
• NCBI Gene ID: 5733
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43115
  UNIPROT ID#>>O00325
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prostaglandin E receptor 3 interacts with:

• ADAMTS like 4
  adaptor related protein complex 3 subunit beta 1
  ADP ribosylation factor like GTPase 10
  alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  ankyrin repeat domain 13D
  armadillo repeat containing X-linked 3
  C2 calcium dependent domain containing 5
  cellular inhibitor of PP2A
  chromosome 1 open reading frame 112
  CKLF like MARVEL transmembrane domain containing 4
  coiled-coil domain containing 33
  cullin associated and neddylation dissociated 2 (putative)
  CWC22 spliceosome associated protein homolog
  cysteine rich with EGF like domains 1
  dedicator of cytokinesis 7
  dehydrogenase/reductase 7
  disco interacting protein 2 homolog A
  dymeclin
  ecdysoneless cell cycle regulator
  ecotropic viral integration site 5 like
  EGF containing fibulin extracellular matrix protein 2
  eukaryotic translation initiation factor 2B subunit beta
  eukaryotic translation initiation factor 2B subunit delta
  eukaryotic translation initiation factor 2B subunit epsilon
  eukaryotic translation initiation factor 2B subunit gamma
  exocyst complex component 2
  exportin 4
  family with sequence similarity 189 member B
  FERM, ARH/RhoGEF and pleckstrin domain protein 2
  gem nuclear organelle associated protein 4
  ghrelin and obestatin prepropeptide
  HEAT repeat containing 3
  hook microtubule tethering protein 2
  importin 11
  importin 7
  importin 8
  importin 9
  inhibitor of CDK, cyclin A1 interacting protein 1
  keratin 38
  keratin 40
  keratin associated protein 10-3
  keratin associated protein 10-7
  keratin associated protein 10-8
  keratin associated protein 10-9
  leucine rich repeats and immunoglobulin like domains 3
  limb development membrane protein 1
  lipolysis stimulated lipoprotein receptor
  mitogen-activated protein kinase kinase kinase kinase 4
  mitoguardin 1
  myeloid associated differentiation marker
  NOP9 nucleolar protein
  notch 2 N-terminal like A
  NUS1 dehydrodolichyl diphosphate synthase subunit
  oxysterol binding protein like 8
  PBX homeobox interacting protein 1
  phospholipase C beta 1
  plakophilin 4
  pleckstrin homology and RhoGEF domain containing G4
  pleckstrin homology like domain family B member 3
  pleckstrin homology, MyTH4 and FERM domain containing H3
  protein kinase N3
  protein phosphatase 1 regulatory subunit 15B
  RAB18, member RAS oncogene family
  regulator of G protein signaling 17
  regulator of G protein signaling 20
  REL proto-oncogene, NF-kB subunit
  retinol saturase
  rhomboid 5 homolog 2
  RNA binding protein with serine rich domain 1
  serum amyloid A like 1
  solute carrier family 39 member 1
  solute carrier family 9 member A1
  sprouty RTK signaling antagonist 2
  stromal antigen 1
  suppression of tumorigenicity 7
  TBC1 domain family member 15
  transcription factor 4
  transmembrane p24 trafficking protein family member 8
  transmembrane protein 94
  transportin 2
  transportin 3
  tripartite motif containing 42
  tRNA-yW synthesizing protein 1 homolog B
  tubulin gamma complex associated protein 2
  ubiquitin specific peptidase 46
  upstream binding transcription factor
  VANGL planar cell polarity protein 2
  VPS8 subunit of CORVET complex
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.