SMC4, structural maintenance of chromosomes 4

SMC4, structural maintenance of chromosomes 4

• This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2. [provided by RefSeq, Jun 2016]

• Gene Synonyms (structural maintenance of chromosomes protein 4, SMC protein 4, SMC4 structural maintenance of chromosomes 4-like 1, chromosome-associated polypeptide C, CAP-C, CAPC, SMC-4, SMC4L1,)
• NCBI Gene ID: 10051
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E9PD53
  UNIPROT ID#>>B3KXX5
  UNIPROT ID#>>Q58F29
  UNIPROT ID#>>Q9NTJ3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

structural maintenance of chromosomes 4 interacts with:

• aldehyde dehydrogenase 8 family member A1
  autophagy related 16 like 1
  BCL6 corepressor
  bromodomain containing 7
  cell cycle and apoptosis regulator 2
  checkpoint kinase 2
  coiled-coil domain containing 8
  DNA topoisomerase II binding protein 1
  dual specificity phosphatase 15
  egl-9 family hypoxia inducible factor 3
  F-box protein 6
  forkhead box B1
  forkhead box Q1
  G3BP stress granule assembly factor 1
  glutamate rich WD repeat containing 1
  HECT domain E3 ubiquitin protein ligase 1
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 11
  inturned planar cell polarity protein
  kinesin family member 2C
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat containing G protein-coupled receptor 4
  ligand of numb-protein X 1
  limb development membrane protein 1 like
  methylphosphate capping enzyme
  non-SMC condensin I complex subunit G
  non-SMC condensin I complex subunit H
  non-SMC condensin I complex, subunit H
  non-SMC condensin II complex subunit D3
  non-SMC condensin II complex subunit H2
  non-SMC condensin II complex, subunit G2
  nuclear factor, erythroid derived 2, like 2
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  potassium channel tetramerisation domain containing 5
  pre-mRNA processing factor 8
  PTEN induced kinase 1
  RAB, member RAS oncogene family like 6
  ring finger protein 123
  RIO kinase 1
  SAC1 suppressor of actin mutations 1-like (yeast)
  sirtuin 6
  sirtuin 7
  SNW domain containing 1
  spindle apparatus coiled-coil protein 1
  structural maintenance of chromosomes 2
  SUZ12 polycomb repressive complex 2 subunit
  TNF superfamily member 13b
  TRAF3 interacting protein 1
  tripartite motif containing 28
  tripartite motif containing 29
  unc-93 homolog B1, TLR signaling regulator
  vir like m6A methyltransferase associated
  WD repeat domain 76
  zinc finger and BTB domain containing 7A
  zinc finger protein 598, E3 ubiquitin ligase
  zinc ribbon domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.