OS9, OS9 endoplasmic reticulum lectin

OS9, OS9 endoplasmic reticulum lectin

• This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ERLEC2, OS-9, protein OS-9, amplified in osteosarcoma 9, endoplasmic reticulum lectin 2, erlectin 2, osteosarcoma amplified 9, endoplasmic reticulum associated protein, osteosarcoma amplified 9, endoplasmic reticulum lectin,)
• NCBI Gene ID: 10956
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13438
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

OS9 endoplasmic reticulum lectin interacts with:

• activating transcription factor 6
  agrin
  assembly factor for spindle microtubules
  beta-1,3-N-acetylgalactosaminyltransferase 2
  calreticulin 3
  cerebral endothelial cell adhesion molecule
  collagen beta(1-O)galactosyltransferase 1
  collagen beta(1-O)galactosyltransferase 2
  contactin associated protein family member 3
  cyclin J like
  defensin beta 121
  dendrocyte expressed seven transmembrane protein
  derlin 2
  dipeptidase 2
  DnaJ heat shock protein family (Hsp40) member B11
  egl-9 family hypoxia inducible factor 1
  egl-9 family hypoxia inducible factor 3
  elastin microfibril interfacer 2
  embigin
  endoplasmic reticulum lectin 1
  ER degradation enhancing alpha-mannosidase like protein 2
  ER degradation enhancing alpha-mannosidase like protein 3
  FAD dependent oxidoreductase domain containing 2
  family with sequence similarity 8 member A1
  Fas associated factor family member 2
  F-box protein 15
  F-box protein 6
  Fraser extracellular matrix complex subunit 1
  interleukin 17 receptor A
  kallikrein related peptidase 5
  laminin subunit alpha 1
  lon peptidase 2, peroxisomal
  lysozyme like 2
  N-acylethanolamine acid amidase
  nicastrin
  nucleoporin 210
  OS9 endoplasmic reticulum lectin
  podocan
  polypeptide N-acetylgalactosaminyltransferase 18
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  sel-1 suppressor of lin-12-like (C. elegans)
  selenoprotein N
  SID1 transmembrane family, member 2
  solute carrier family 12, member 1
  solute carrier family 12, member 3
  store-operated calcium entry associated regulatory factor
  sulfatase 2
  synoviolin 1
  tectonic family member 1
  tetratricopeptide repeat domain 17
  thioredoxin domain containing 11
  thioredoxin domain containing 16
  transient receptor potential cation channel subfamily V member 4
  transmembrane O-mannosyltransferase targeting cadherins 4
  transmembrane protein 131
  ubiquitin conjugating enzyme E2 J1
  UDP glucuronosyltransferase family 1 member A10
  UDP-glucose glycoprotein glucosyltransferase 2
  unc-93 homolog B1, TLR signaling regulator
  zinc finger NFX1-type containing 1
  zinc finger protein 512B
  zona pellucida binding protein 2
  zyg-11 family member B, cell cycle regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.