TUBB2A, tubulin beta 2A class IIa

TUBB2A, tubulin beta 2A class IIa

• Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

• Gene Synonyms (tubulin beta-2A chain, class IIa beta-tubulin, tubulin, beta 2A, tubulin, beta polypeptide 2, CDCBM5, TUBB, TUBB2,)
• NCBI Gene ID: 7280
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13885
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tubulin beta 2A class IIa interacts with:

• 3'-phosphoadenosine 5'-phosphosulfate synthase 2
  AAR2 splicing factor
  ACD shelterin complex subunit and telomerase recruitment factor
  activator of HSP90 ATPase activity 1
  ADP ribosylation factor like GTPase 15
  alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
  ankyrin repeat and SOCS box containing 4
  anterior gradient 2, protein disulphide isomerase family member
  argonaute RISC catalytic component 3
  BCL2 like 14
  bromodomain containing 7
  centrosomal protein 76
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 6B
  chaperonin containing Tcp1, subunit 3 (gamma)
  coiled-coil domain containing 8
  cullin 2
  cullin 3
  cytosolic iron-sulfur assembly component 2B
  DISC1 scaffold protein
  EEF1A lysine methyltransferase 3
  egl-9 family hypoxia inducible factor 3
  electron transfer flavoprotein subunit beta lysine methyltransferase
  EMAP like 2
  EMAP like 4
  family with sequence similarity 86 member B2
  Fas associated factor 1
  F-box and WD repeat domain containing 7
  F-box protein 25
  F-box protein 7
  glycosylated lysosomal membrane protein
  H4 clustered histone 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  hepatocyte growth factor-regulated tyrosine kinase substrate
  hes related family bHLH transcription factor with YRPW motif 1
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 4
  histone deacetylase 6
  IQ motif containing B1
  La ribonucleoprotein 7, transcriptional regulator
  large tumor suppressor kinase 2
  limb development membrane protein 1 like
  lysosomal associated membrane protein 3
  methylphosphate capping enzyme
  methyltransferase like 21C
  methyltransferase like 22
  methyltransferase like 23
  methyltransferase like 3
  mortality factor 4 like 1
  mortality factor 4 like 2
  MRG domain binding protein
  myosin, heavy polypeptide 9, non-muscle
  NSFL1 cofactor
  obscurin like cytoskeletal adaptor 1
  PDZ and LIM domain 5
  phospholipase A2 activating protein
  pleckstrin homology domain containing A4
  protection of telomeres 1
  protein phosphatase, Mg2+/Mn2+ dependent 1D
  protein tyrosine phosphatase non-receptor type 18
  Rab acceptor 1
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  regulator of chromosome condensation 1
  RIC8 guanine nucleotide exchange factor A
  sequestosome 1
  sirtuin 6
  solute carrier family 15 member 3
  SSX family member 2 interacting protein
  syndecan 3
  testin LIM domain protein
  tetratricopeptide repeat domain 5
  thioredoxin domain containing 9
  TRAF2 and NCK interacting kinase
  TRAF3 interacting protein 1
  tripartite motif containing 14
  tripartite motif containing 25
  tryptase beta 2
  Tu translation elongation factor, mitochondrial
  tubulin alpha 1a
  tubulin alpha 1b
  tubulin alpha 1c
  tubulin beta 3 class III
  tubulin beta 4B class IVb
  tubulin beta 8 class VIII
  tubulin beta class I
  tubulin gamma complex associated protein 2
  tubulin gamma complex associated protein 4
  twinfilin actin binding protein 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquitin specific peptidase 14
  UBX domain protein 1
  unc-93 homolog B1, TLR signaling regulator
  UPF2 regulator of nonsense mediated mRNA decay
  valosin containing protein lysine methyltransferase
  voltage dependent anion channel 1
  WD repeat domain 77
  Yes1 associated transcriptional regulator
  zinc finger containing ubiquitin peptidase 1
  zinc finger protein 146
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.