TUFM, Tu translation elongation factor, mitochondrial

TUFM, Tu translation elongation factor, mitochondrial

• This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]

• Gene Synonyms (elongation factor Tu, mitochondrial, EF-Tu, epididymis secretory sperm binding protein, COXPD4, EF-TuMT, EFTU, P43,)
• NCBI Gene ID: 7284
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49411
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Tu translation elongation factor, mitochondrial interacts with:

• 5'-nucleotidase, cytosolic IIIA
  AAR2 splicing factor
  ADP ribosylation factor like GTPase 6 interacting protein 1
  alkylglycerone phosphate synthase
  ankyrin repeat and SOCS box containing 10
  ankyrin repeat and SOCS box containing 12
  ankyrin repeat and SOCS box containing 14
  ankyrin repeat and SOCS box containing 17
  anterior gradient 2, protein disulphide isomerase family member
  apoptosis inducing factor mitochondria associated 1
  argonaute RISC component 4
  armadillo repeat containing 12
  armadillo repeat containing 8
  autophagy and beclin 1 regulator 1
  autophagy related 16 like 1
  BAF nuclear assembly factor 1
  BCL2 like 14
  beclin 1
  bromodomain containing 7
  calcium/calmodulin dependent protein kinase ID
  caveolae associated protein 3
  CCCTC-binding factor
  charged multivesicular body protein 7
  CKLF like MARVEL transmembrane domain containing 5
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  COPI coat complex subunit epsilon
  coronin 1C
  cullin 2
  cullin 3
  cullin 4B
  cullin 5
  cullin 7
  cytochrome c oxidase assembly factor 3
  cytoskeleton associated protein 5
  decapping enzyme, scavenger
  DExD-box helicase 39B
  diacylglycerol O-acyltransferase 2 like 6
  dickkopf like acrosomal protein 1
  egl-9 family hypoxia inducible factor 3
  elongation factor Tu GTP binding domain containing 2
  ER membrane protein complex subunit 2
  exosome component 6
  exportin 1
  family with sequence similarity 9 member B
  Fas associated factor 1
  F-box protein 6
  FUN14 domain containing 1
  G elongation factor mitochondrial 1
  G3BP stress granule assembly factor 1
  general transcription factor IIIC subunit 4
  GTP dependent ribosome recycling factor mitochondrial 2
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  histone deacetylase 5
  homeobox containing 1
  huntingtin interacting protein 1 related
  importin 9
  isoleucyl-tRNA synthetase 2, mitochondrial
  lactamase beta
  leucine rich repeat containing 59
  limb development membrane protein 1 like
  metadherin
  methylcrotonoyl-CoA carboxylase 1
  methylphosphate capping enzyme
  methyltransferase like 14
  methyltransferase like 3
  mitochondrial ribosomal protein L1
  mitochondrial ribosomal protein L11
  mitochondrial ribosomal protein L14
  mitochondrial ribosomal protein L17
  mitochondrial ribosomal protein L18
  mitochondrial ribosomal protein L2
  mitochondrial ribosomal protein L22
  mitochondrial ribosomal protein L24
  mitochondrial ribosomal protein L3
  mitochondrial ribosomal protein L4
  mitochondrial ribosomal protein S10
  mitochondrial ribosomal protein S14
  mitochondrial ribosomal protein S5
  mitochondrial ribosomal protein S7
  mitochondrial translational initiation factor 3
  mucin 20, cell surface associated
  NADH:ubiquinone oxidoreductase core subunit S7
  nascent polypeptide associated complex subunit alpha 2
  NEDD8 activating enzyme E1 subunit 1
  neudesin neurotrophic factor
  nicotinamide nucleotide transhydrogenase
  NOP56 ribonucleoprotein
  NSFL1 cofactor
  obscurin like cytoskeletal adaptor 1
  palmitoyl-protein thioesterase 2
  PHD finger protein 19
  phospholipase A2 activating protein
  pleckstrin homology domain containing A4
  poly(A) specific ribonuclease subunit PAN2
  PR/SET domain 16
  prohibitin 2
  protein disulfide isomerase family A member 4
  pseudouridine synthase 1
  PTEN induced kinase 1
  pyridoxal phosphate binding protein
  RecQ like helicase 4
  regulatory associated protein of MTOR complex 1
  rhomboid domain containing 2
  ribosomal protein L14
  ribosomal protein L23
  ring finger protein 123
  ring-box 1
  RIO kinase 1
  RNA polymerase III subunit A
  selenophosphate synthetase 1
  seryl-tRNA synthetase 2, mitochondrial
  sideroflexin 3
  sirtuin 7
  SMAD specific E3 ubiquitin protein ligase 1
  solute carrier family 25 member 24
  SprT-like N-terminal domain
  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
  SUZ12 polycomb repressive complex 2 subunit
  testin LIM domain protein
  testis specific serine kinase 1B
  TNF receptor superfamily member 10a
  TNF receptor superfamily member 10d
  TNFAIP3 interacting protein 2
  transmembrane protein 41B
  tripartite motif containing 28
  tubulin alpha 1a
  tubulin beta 6 class V
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin C
  ubiquitin like 4A
  ubiquitin specific peptidase 5
  UBX domain protein 1
  valosin containing protein
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  WD repeat domain 12
  WT1 associated protein
  Yes1 associated transcriptional regulator
  zinc finger DHHC-type palmitoyltransferase 15
  zinc finger MYM-type containing 6
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746
  zinc finger SWIM-type containing 7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.