UQCRC2, ubiquinol-cytochrome c reductase core protein 2

UQCRC2, ubiquinol-cytochrome c reductase core protein 2

• The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]

• Gene Synonyms (cytochrome b-c1 complex subunit 2, mitochondrial, complex III subunit 2, cytochrome bc-1 complex core protein II, ubiquinol-cytochrome c reductase core protein II, ubiquinol-cytochrome-c reductase complex core protein 2, MC3DN5, QCR2, UQCR2,)
• NCBI Gene ID: 7385
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P22695
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquinol-cytochrome c reductase core protein 2 interacts with:

• AAR2 splicing factor
  AFG3 like matrix AAA peptidase subunit 2
  AKT interacting protein
  alkylglycerone phosphate synthase
  ankyrin repeat domain 34C
  apoptosis inducing factor mitochondria associated 1
  armadillo repeat containing X-linked 3
  ATPase family AAA domain containing 3A
  calreticulin 3
  CDGSH iron sulfur domain 3
  chaperonin containing TCP1 subunit 6B
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  chromosome 15 open reading frame 48
  coenzyme Q9
  coiled-coil domain containing 8
  coronin 1C
  c-src tyrosine kinase
  cytochrome b5 reductase 1
  cytochrome c oxidase assembly factor 3
  cytochrome c oxidase subunit 5A
  cytochrome c oxidase subunit 7A2 like
  damage specific DNA binding protein 1
  DExD-box helicase 39B
  dual specificity phosphatase 21
  egl-9 family hypoxia inducible factor 3
  EH domain containing 4
  ER membrane protein complex subunit 2
  ER membrane protein complex subunit 4
  ER membrane protein complex subunit 8
  excision repair cross-complementing rodent repair deficiency complementation group 6 like
  Fas associated factor family member 2
  F-box protein 6
  FKBP prolyl isomerase 10
  FKBP prolyl isomerase 8
  glucosidase II alpha subunit
  golgi transport 1B
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  heterogeneous nuclear ribonucleoprotein A3
  histone deacetylase 5
  huntingtin
  hydroxysteroid 17-beta dehydrogenase 12
  inner membrane mitochondrial protein
  interferon induced transmembrane protein 3
  lactamase beta
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
  leucine rich pentatricopeptide repeat containing
  leucine rich repeat containing 59
  lon peptidase 1, mitochondrial
  mitochondrial carrier 2
  mitochondrial ribosomal protein L37
  myosin light chain 12A
  NADH:ubiquinone oxidoreductase core subunit S7
  NADH:ubiquinone oxidoreductase subunit A12
  neutrophil cytosolic factor 1
  nicotinamide nucleotide transhydrogenase
  nipsnap homolog 1
  OCIA domain containing 1
  peroxiredoxin 3
  pleckstrin homology domain containing A4
  prohibitin 2
  prostaglandin E synthase 2
  protein phosphatase, Mg2+/Mn2+ dependent 1E
  protein tyrosine phosphatase mitochondrial 1
  PTEN induced kinase 1
  RAB10, member RAS oncogene family
  RAB1B, member RAS oncogene family
  RAB5 interacting factor
  RAB6B, member RAS oncogene family
  RAB7A, member RAS oncogene family
  receptor interacting serine/threonine kinase 4
  RecQ like helicase 4
  regulator of microtubule dynamics 3
  reticulon 4
  ring-box 1
  saccharopine dehydrogenase (putative)
  SEC61 translocon subunit alpha 1
  sideroflexin 1
  sirtuin 7
  SLX1 homolog B, structure-specific endonuclease subunit
  solute carrier family 25 member 24
  solute carrier family 25 member 28
  stearoyl-CoA desaturase 5
  sulfide quinone oxidoreductase
  TAR DNA binding protein
  testis expressed 101
  trans-2,3-enoyl-CoA reductase
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 5
  translocase of outer mitochondrial membrane 6
  transmembrane and coiled-coil domains 1
  transmembrane protein 41B
  tripartite motif containing 28
  ubiquinol-cytochrome c reductase complex III subunit VII
  ubiquinol-cytochrome c reductase hinge protein
  ubiquitin protein ligase E3 component n-recognin 5
  valosin containing protein
  VAMP associated protein A
  VAMP associated protein B and C
  vir like m6A methyltransferase associated
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  Yes1 associated transcriptional regulator
  zinc finger protein 326
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746
  zinc finger protein 782

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.