NOP56, NOP56 ribonucleoprotein

NOP56, NOP56 ribonucleoprotein

• Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016]

• Gene Synonyms (NOL5A, SCA36, nucleolar protein 56, NOP56 ribonucleoprotein homolog, nucleolar protein 5A (56kDa with KKE/D repeat),)
• NCBI Gene ID: 10528
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00567
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NOP56 ribonucleoprotein interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  ATPase family AAA domain containing 3B
  ATPase family AAA domain containing 5
  BCL6 corepressor
  biogenesis of ribosomes BRX1
  BOP1 ribosomal biogenesis factor
  bromodomain containing 7
  caveolae associated protein 1
  centromere protein V
  chromosome 12 open reading frame 43
  chromosome 7 open reading frame 50
  chromosome 8 open reading frame 33
  coenzyme Q2, polyprenyltransferase
  coiled-coil domain containing 124
  coiled-coil domain containing 137
  coiled-coil domain containing 8
  coiled-coil domain containing 86
  COP9 signalosome subunit 5
  cullin associated and neddylation dissociated 1
  DDB1 and CUL4 associated factor 13
  DEAD-box helicase 24
  DEAD-box helicase 27
  DEAD-box helicase 54
  DEAD-box helicase 55
  DEAD-box helicase 56
  DEAH-box helicase 33
  DEAH-box helicase 37
  decapping enzyme, scavenger
  developmental pluripotency-associated 3
  DExD-box helicase 50
  DExH-box helicase 30
  DExH-box helicase 57
  DISC1 scaffold protein
  DnaJ heat shock protein family (Hsp40) member C17
  dynein cytoplasmic 1 light intermediate chain 1
  EBNA1 binding protein 2
  exosome component 4
  extended synaptotagmin 2
  family with sequence similarity 111 member A
  fibrillarin
  FMR1 neighbor
  FtsJ RNA 2'-O-methyltransferase 3
  G protein nucleolar 3
  glyoxylate reductase 1 homolog
  G-patch domain containing 4
  GTP binding protein 4
  histone deacetylase 11
  IMP U3 small nucleolar ribonucleoprotein 4
  inhibitor of Bruton tyrosine kinase
  inhibitory synaptic factor 2A
  insulin like growth factor 2 mRNA binding protein 1
  jade family PHD finger 2
  karyopherin subunit alpha 6
  KRI1 homolog
  KRR1 small subunit processome component homolog
  L3MBTL histone methyl-lysine binding protein 1
  La ribonucleoprotein 1, translational regulator
  La ribonucleoprotein 7, transcriptional regulator
  large 60S subunit nuclear export GTPase 1
  LBH domain containing 1
  LEM domain nuclear envelope protein 2
  LUC7 like 2, pre-mRNA splicing factor
  Ly1 antibody reactive
  mediator complex subunit 4
  methylphosphate capping enzyme
  methyltransferase like 14
  minichromosome maintenance 9 homologous recombination repair factor
  mitochondrial rRNA methyltransferase 1
  MRT4 homolog, ribosome maturation factor
  N-acetyltransferase 10
  neurogenin 3
  nicastrin
  NOC2 like nucleolar associated transcriptional repressor
  NOP10 ribonucleoprotein
  NOP16 nucleolar protein
  NOP58 ribonucleoprotein
  nucleolar pre-rRNA processing protein NIP7
  nucleolar protein 6
  nucleolar protein interacting with the FHA domain of MKI67
  obscurin like cytoskeletal adaptor 1
  pelota mRNA surveillance and ribosome rescue factor
  pescadillo ribosomal biogenesis factor 1
  peter pan homolog
  PIN2 (TERF1) interacting telomerase inhibitor 1
  PNMA family member 3
  polycomb group ring finger 1
  POP1 homolog, ribonuclease P/MRP subunit
  PR/SET domain 16
  PWP1 homolog, endonuclein
  RAD18 E3 ubiquitin protein ligase
  regulatory associated protein of MTOR complex 1
  ribosomal L1 domain containing 1
  ribosomal oxygenase 1
  ribosomal oxygenase 2
  ribosomal protein L13a
  ribosomal protein L36
  ribosomal RNA processing 12 homolog
  ribosomal RNA processing 15 homolog
  ribosome binding protein 1
  ribosome biogenesis regulator 1 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RNA binding motif protein 28
  RNA binding motif protein 34
  RNA polymerase I subunit B
  RNA transcription, translation and transport factor
  SCY1 like pseudokinase 2
  signal recognition particle 72
  sirtuin 7
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  SRSF protein kinase 3
  sterile alpha motif domain containing 1
  suppressor of glucose, autophagy associated 1
  syndecan binding protein 2
  TAR DNA binding protein
  THAP domain containing 7
  TNF receptor superfamily member 19
  transducin beta like 3
  tRNA methyltransferase 10C, mitochondrial RNase P subunit
  tRNA methyltransferase subunit 11-2
  TSR1 ribosome maturation factor
  tubulin beta 1 class VI
  U2 small nuclear RNA auxiliary factor 2
  UTP14A small subunit processome component
  UTP18 small subunit processome component
  UTP20 small subunit processome component
  UTP4 small subunit processome component
  WD repeat domain 3
  WD repeat domain 36
  WD repeat domain 74
  WD repeat domain 76
  WW domain containing oxidoreductase
  Y box protein 1
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.