UBE2N, ubiquitin conjugating enzyme E2 N

UBE2N, ubiquitin conjugating enzyme E2 N

• The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ubiquitin-conjugating enzyme E2 N, E2 ubiquitin-conjugating enzyme N, bendless-like ubiquitin conjugating enzyme, epididymis secretory protein Li 71, ubiquitin carrier protein N, ubiquitin conjugating enzyme E2N, ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13), ubiquitin-protein ligase N, yeast UBC13 homolog, HEL-S-71, UBC13, UBCHBEN; UBC13, UbcH-ben, UbcH13,)
• NCBI Gene ID: 7334
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HW41
  UNIPROT ID#>>P61088
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin conjugating enzyme E2 N interacts with:

• AAR2 splicing factor
  actin related protein 2
  actin related protein 2/3 complex subunit 4
  acyl-CoA thioesterase 13
  adhesion regulating molecule 1
  aminoacyl tRNA synthetase complex interacting multifunctional protein 1
  apoptosis inducing factor mitochondria associated 1
  ariadne RBR E3 ubiquitin protein ligase 1
  ariadne RBR E3 ubiquitin protein ligase 2
  aspartate dehydrogenase domain containing
  ATPase H+ transporting V1 subunit H
  BAG cochaperone 3
  BCL10 immune signaling adaptor
  bifunctional apoptosis regulator
  calcium binding protein 39
  calcium dependent secretion activator 2
  checkpoint with forkhead and ring finger domains
  cleavage and polyadenylation specific factor 6
  copine 3
  cornulin
  CTD nuclear envelope phosphatase 1 regulatory subunit 1
  cysteine rich hydrophobic domain 2
  cytochrome c, somatic
  DAZ interacting zinc finger protein 3
  denticleless E3 ubiquitin protein ligase homolog
  derlin 1
  DnaJ heat shock protein family (Hsp40) member C8
  elongation factor Tu GTP binding domain containing 2
  EPM2A glucan phosphatase, laforin
  eukaryotic translation initiation factor 3 subunit M
  eukaryotic translation initiation factor 5B
  F-box and WD repeat domain containing 7
  glucosamine-phosphate N-acetyltransferase 1
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  heterogeneous nuclear ribonucleoprotein A3
  HEXIM P-TEFb complex subunit 1
  ISG15 ubiquitin like modifier
  kinesin family member 1C
  lactate dehydrogenase A like 6A
  leucine rich repeat and sterile alpha motif containing 1
  leucine rich repeat kinase 2
  ligand of numb-protein X 1
  makorin ring finger protein 3
  MALT1 paracaspase
  mediator complex subunit 15
  meiosis specific nuclear structural 1
  membrane associated ring-CH-type finger 5
  membrane associated ring-CH-type finger 7
  mex-3 RNA binding family member C
  midline 2
  mindbomb E3 ubiquitin protein ligase 1
  mindbomb E3 ubiquitin protein ligase 2
  mitochondrial E3 ubiquitin protein ligase 1
  mitofusin 2
  myosin light chain 12B
  myosin regulatory light chain interacting protein
  N-acetylneuraminate synthase
  NEDD4 like E3 ubiquitin protein ligase
  neuralized E3 ubiquitin protein ligase 1
  NHL repeat containing E3 ubiquitin protein ligase 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  PEDS1-UBE2V1 readthrough
  pellino E3 ubiquitin protein ligase 1
  pellino E3 ubiquitin protein ligase family member 3
  phosphoethanolamine/phosphocholine phosphatase 1
  phosphoglycerate dehydrogenase
  PIH1 domain containing 1
  plasmanylethanolamine desaturase 1
  praja ring finger ubiquitin ligase 2
  pre-mRNA processing factor 31
  PTTG1 regulator of sister chromatid separation, securin
  RAD9-HUS1-RAD1 interacting nuclear orphan 1
  RANBP2-type and C3HC4-type zinc finger containing 1
  receptor interacting serine/threonine kinase 1
  rhomboid 5 homolog 2
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  ring finger and WD repeat domain 3
  ring finger protein 103
  ring finger protein 11
  ring finger protein 111
  ring finger protein 115
  ring finger protein 122
  ring finger protein 123
  ring finger protein 125
  ring finger protein 126
  ring finger protein 128
  ring finger protein 13
  ring finger protein 130
  ring finger protein 135
  ring finger protein 152
  ring finger protein 165
  ring finger protein 167
  ring finger protein 168
  ring finger protein 181
  ring finger protein 182
  ring finger protein 43
  ring finger protein 8
  SH3 domain containing ring finger 1
  SH3 domain containing ring finger 2
  SHH signaling and ciliogenesis regulator SDCCAG8
  sirtuin 1
  SNF2 histone linker PHD RING helicase
  SNW domain containing 1
  splicing factor 1
  splicing factor 3a subunit 1
  splicing factor 3a subunit 3
  STAM binding protein like 1
  staphylococcal nuclease and tudor domain containing 1
  STIP1 homology and U-box containing protein 1
  STIP1 homology and U-Box containing protein 1
  SUZ12 polycomb repressive complex 2 subunit
  thioredoxin domain containing 17
  TNF receptor associated protein 1
  TNF receptor-associated factor 6
  TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  tripartite motif containing 11
  tripartite motif containing 14
  tripartite motif containing 17
  tripartite motif containing 25
  tripartite motif containing 28
  tripartite motif containing 32
  tripartite motif containing 33
  tripartite motif containing 39
  tripartite motif containing 5
  tripartite motif containing 50
  tripartite motif containing 54
  tripartite motif containing 63
  tripartite motif containing 69
  tripartite motif containing 72
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 V1
  ubiquitin conjugating enzyme E2 V2
  ubiquitin like 5
  ubiquitin like with PHD and ring finger domains 1
  ubiquitin protein ligase E3A
  ubiquitin recognition factor in ER associated degradation 1
  ubiquitin specific peptidase 14
  vascular cell adhesion molecule 1
  vasodilator stimulated phosphoprotein
  vimentin
  vinculin
  VPS33B late endosome and lysosome associated
  zinc and ring finger 1
  zinc and ring finger 2
  zinc and ring finger 3
  zinc and ring finger 4
  zinc finger DHHC-type palmitoyltransferase 5
  zinc finger protein 207
  zyxin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.