BAG6, BAG cochaperone 6

BAG6, BAG cochaperone 6

• This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (large proline-rich protein BAG6, BAG family molecular chaperone regulator 6, BCL2 associated athanogene 6, HLA-B-associated transcript 3, large proline-rich protein BAT3, protein G3, protein Scythe, scythe, BAG-6, BAT3, D6S52E, G3,)
• NCBI Gene ID: 7917
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P46379
  UNIPROT ID#>>A0A1U9X7A6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BAG cochaperone 6 interacts with:

• 5'-3' exoribonuclease 1
  AAR2 splicing factor
  actin related protein 2/3 complex subunit 3
  actin related protein 8
  activating signal cointegrator 1 complex subunit 2
  adenine nucleotide translocase lysine methyltransferase
  amelotin
  amyloid beta precursor protein binding family B member 1 interacting protein
  apoptosis inducing factor mitochondria associated 1
  autophagy and beclin 1 regulator 1
  BAG cochaperone 6
  BAR/IMD domain containing adaptor protein 2 like 1
  C2 calcium dependent domain containing 5
  cancer/testis antigen 1A
  CCAAT enhancer binding protein zeta
  CCCTC-binding factor like
  CCR4-NOT transcription complex subunit 1
  CD93 molecule
  cell division cycle associated 5
  centriolin
  centrosomal protein 55
  ceramide kinase
  charged multivesicular body protein 5
  ciliogenesis associated kinase 1
  coiled-coil domain containing 88A
  cullin 7
  cyclin B1 interacting protein 1
  cyclin Q
  cysteine rich tail 1
  derlin 2
  dermokine
  desumoylating isopeptidase 1
  DnaJ heat shock protein family (Hsp40) member A4
  DnaJ heat shock protein family (Hsp40) member B11
  DOT1 like histone lysine methyltransferase
  EEF1A lysine methyltransferase 3
  EGF containing fibulin extracellular matrix protein 2
  egl-9 family hypoxia inducible factor 3
  elongator complex protein 1
  enolase-phosphatase 1
  eukaryotic translation initiation factor 3 subunit H
  FA complementation group L
  family with sequence similarity 9 member B
  Fas associated factor 1
  Fas associated factor family member 2
  F-box protein 38
  F-box protein 7
  fibronectin type III domain containing 3A
  frizzled class receptor 4
  fuzzy planar cell polarity protein
  glutamate rich WD repeat containing 1
  golgi to ER traffic protein 4
  golgin A6 family like 9
  GTF2I repeat domain containing 1
  guided entry of tail-anchored proteins factor 3, ATPase
  guided entry of tail-anchored proteins factor 4
  H3 clustered histone 14
  HECT domain E3 ubiquitin protein ligase 3
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  hepatitis A virus cellular receptor 2
  HEXIM P-TEFb complex subunit 1
  immediate early response 3
  importin 4
  inner membrane mitochondrial protein
  inositol hexakisphosphate kinase 3
  insulin induced gene 2
  interferon induced transmembrane protein 3
  interleukin 17 receptor C
  IQ motif containing G
  kelch like family member 12
  kinesin family member 21B
  kinesin light chain 3
  late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
  limb development membrane protein 1 like
  MAGE family member D1
  mediator complex subunit 20
  mediator complex subunit 23
  mediator complex subunit 4
  metastasis associated 1
  methyltransferase like 23
  methyltransferase like 3
  microtubule actin crosslinking factor 1
  mitochondrial antiviral signaling protein
  mitochondrial ribosomal protein L17
  mitochondrial ribosomal protein L55
  myeloid derived growth factor
  myoferlin
  myopalladin
  myosin, heavy polypeptide 9, non-muscle
  NADH:ubiquinone oxidoreductase subunit B11
  natural cytotoxicity triggering receptor 3
  NODAL modulator 1
  NODAL modulator 3
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  oxidative stress responsive kinase 1
  oxysterol binding protein like 2
  palmdelphin
  PAS domain containing serine/threonine kinase
  patatin like phospholipase domain containing 8
  penta-EF-hand domain containing 1
  peptide deformylase, mitochondrial
  peptidylprolyl isomerase like 3
  phosphodiesterase 12
  phospholipid phosphatase 2
  phospholipid phosphatase related 3
  plexin A3
  potassium voltage-gated channel subfamily A regulatory beta subunit 2
  pre-mRNA processing factor 40 homolog A
  programmed cell death 11
  proline, glutamate and leucine rich protein 1
  proteasome 26S subunit, non-ATPase 14
  protein phosphatase 4 regulatory subunit 3B
  PTEN induced kinase 1
  PTTG1 regulator of sister chromatid separation, securin
  RAB10, member RAS oncogene family
  RAB14, member RAS oncogene family
  RAB15, member RAS oncogene family
  RAB1B, member RAS oncogene family
  RAB2B, member RAS oncogene family
  RAB6B, member RAS oncogene family
  RAB9B, member RAS oncogene family
  RAD54 like
  receptor accessory protein 3
  receptor interacting serine/threonine kinase 4
  regulatory factor X associated ankyrin containing protein
  required for meiotic nuclear division 5 homolog A
  ribonucleoprotein, PTB binding 1
  ribosomal RNA processing 1B
  ring finger protein 115
  ring finger protein 123
  ring finger protein 126
  ring finger protein, LIM domain interacting
  RNA polymerase II associated protein 1
  RNA polymerase III subunit F
  SEC61 translocon subunit alpha 1
  SEC61 translocon subunit beta
  SEM1 26S proteasome complex subunit
  SET binding factor 2
  SET domain bifurcated histone lysine methyltransferase 1
  SHANK associated RH domain interactor
  sirtuin 5
  sirtuin 6
  SMAD family member 3
  small glutamine rich tetratricopeptide repeat containing beta
  spindle apparatus coiled-coil protein 1
  STIP1 homology and U-box containing protein 1
  SUZ12 polycomb repressive complex 2 subunit
  synoviolin 1
  T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
  terminal nucleotidyltransferase 5A
  testin LIM domain protein
  thioredoxin interacting protein
  thyroid hormone receptor interactor 10
  TNFAIP3 interacting protein 2
  TRAF-type zinc finger domain containing 1
  translocase of outer mitochondrial membrane 20
  TRIO and F-actin binding protein
  tripartite motif containing 11
  tripartite motif containing 14
  tRNA splicing endonuclease subunit 2
  TSC22 domain family member 1
  tubulin beta 3 class III
  tumor protein p63
  ubiquilin 1
  ubiquilin 2
  ubiquilin 4
  ubiquitin like 4A
  ubiquitin like 4B
  ubiquitin like 7
  ubiquitin protein ligase E3 component n-recognin 2
  ubiquitin protein ligase E3 component n-recognin 3
  ubiquitin protein ligase E3 component n-recognin 5
  ubiquitin specific peptidase 13
  ubiquitin specific peptidase 15
  ubiquitin specific peptidase 32
  UBX domain protein 1
  UHRF1 binding protein 1
  URB1 ribosome biogenesis homolog
  UV stimulated scaffold protein A
  uveal autoantigen with coiled-coil domains and ankyrin repeats
  VAMP associated protein B and C
  vir like m6A methyltransferase associated
  VPS26, retromer complex component A
  WD repeat and FYVE domain containing 3
  WD repeat and HMG-box DNA binding protein 1
  WD repeat containing, antisense to TP73
  WD repeat domain 83
  WD repeat domain 91
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger AN1-type containing 2B
  zinc finger and BTB domain containing 38
  zinc finger and BTB domain containing 7a
  zinc finger containing ubiquitin peptidase 1
  zinc finger FYVE-type containing 9
  zinc finger protein 286A
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.